Selected Publications

Nkx2.7 is a conserved regulator of craniofacial development

Nature Communications, 16:3802 (2025)

Caitlin Ford, Carmen de Sena-Tomás, Tint Tha Ra Wun, Angelika G. Aleman, Uday Rangaswamy, Jake Leyhr, María I. Nuñez, Cynthia Zehui Gao, Hieu T. Nim, Michael See, Ugo Coppola, Joshua S. Waxman, Mirana Ramialison, Tatjana Haitina, Joanna Smeeton, Remo Sanges & Kimara L. Targoff

Science Advances, 9(7): 4814, 2023.  (PMID: 36800428)
Nicola de Prisco, Caitlin Ford, Nathan D Elrod, Winston Lee, Lauren C Tang, Kai-Lieh Huang, Ai Lin, Ping Ji, Venkata S Jonnakuti, Lia Boyle, Maximilian Cabaj, Salvatore Botta, Katrin Õunap, Karit Reinson, Monica H Wojcik, Jill A Rosenfeld, Weimin Bi, Kristian Tveten, Trine Prescott, Thorsten Gerstner, Audrey Schroeder, Chin-To Fong, Jaya K George-Abraham, Catherine A Buchanan, Andrea Hanson-Khan, Jonathan A Bernstein, Aikaterini A Nella, Wendy K Chung, Vicky Brandt, Marko Jovanovic, Kimara L Targoff, Hari Krishna Yalamanchili, Eric J Wagner, Vincenzo A Gennarino

Science, 380(6649): 9257, 2023. (PMID: 37289866)
Parminder Singh, Kishore Gollapalli, Stefano Mangiola, Daniela Schranner, Mohd Aslam Yusuf, Manish Chamoli, Sting L Shi, Bruno Lopes Bastos, Tripti Nair, Annett Riermeier, Elena M Vayndorf, Judy Z Wu, Aishwarya Nilakhe, Christina Q Nguyen, Michael Muir, Michael G Kiflezghi, Anna Foulger, Alex Junker, Jack Devine, Kunal Sharan, Shankar J Chinta, Swati Rajput, Anand Rane, Philipp Baumert, Martin Schönfelder, Francescopaolo Iavarone, Giorgia Di Lorenzo, Swati Kumari, Alka Gupta, Rajesh Sarkar, Costerwell Khyriem, Amanpreet S Chawla, Ankur Sharma, Nazan Sarper, Naibedya Chattopadhyay, Bichitra K Biswal, Carmine Settembre, Perumal Nagarajan, Kimara L Targoff, Martin Picard, Sarika Gupta, Vidya Velagapudi, Anthony T Papenfuss, Alaattin Kaya, Miguel Godinho Ferreira, Brian K Kennedy, Julie K Andersen, Gordon J Lithgow, Abdullah Mahmood Ali, Arnab Mukhopadhyay, Aarno Palotie, Gabi Kastenmüller, Matt Kaeberlein, Henning Wackerhage, Bhupinder Pal, Vijay K Yadav

Nature Methods, 14: 1054-1062, 2019. (PMID: 31562489)
Venkatakaushik Voleti, Kripa B. Patel, Wenze Li, Citlali Perez Campos, Srinidhi Bharadwaj, Hang Yu, Caitlin Ford, Malte J. Casper, Richard Wenwei Yan, Wenxuan Liang, Chentao Wen, Koutarou D. Kimura, Kimara L. Targoff & Elizabeth M. C. Hillman

Optical Imaging of Metabolic Dynamics in Animals

Nature Communications, August 6th, 2018; 9(1): 2995. (PMID: 30082908)
Lingyan Shi, Chaogu Zheng, Yihui Shen, Zhixing Chen, Edilson S. Silveira, Luyuan Zhang, Mian Wei, Chang Liu, Carmen de Sena-Tomás, Kimara Targoff & Wei Min

nkx Genes Establish SHF Cardiomyocyte Progenitors at the Arterial Pole and Pattern the Venous Pole through Isl1 Repression

Development, February 5th, 2018; 145(3). (PMID: 29361575)
Sophie Colombo, Carmen de Sena-Tomás, Vanessa George, Andreas A. Werdich, Sunil Kapur, Calum A. MacRae, Kimara L. Targoff

Nkx2.5 is Essential to Establish Normal Heart Rate Variability in the Zebrafish Embryo

Am J Physiol Regulatory Integrative Comparative Physiology, June 14th, 2017. (PMID:  28615160)
Jamie K Harrington, Robert Sorabella, Abigail Tercek, Joseph R Isler, Kimara L. Targoff

FGF signaling enforces cardiac chamber identity in the developing ventricle

Development, April 1st, 2017; 144(7): 1328-1338. (PMID: 28232600)
Arjana Pradhan, Xin-Xin I Zeng, Pragya Sidhwani, Sara R Marques, Vanessa George, Kimara L. Targoff, Neil C Chi, Deborah Yelon

Nkx2.5 regulates endothelin converting enzyme-1 during pharyngeal arch patterning

Genesis, Jan. 20th, 2017. (PMID: 28109039)
Jennifer M Iklé, Andre L P Tavares, Marisol King, Hailei Ding, Sophie Colombo, Beth A Firulli, Anthony B Firulli, Kimara L. Targoff, Deborah Yelon, David E Clouthier

Origin, Specification, and Plasticity of the Great Vessels of the Heart

Current Biology, 25(16): 2099-110, 2015. (PMID: 26255850)
Jennifer M Iklé, Andre L P Tavares, Marisol King, Hailei Ding, Sophie Colombo, Beth A Firulli, Anthony B Firulli, Kimara L. Targoff, Deborah Yelon, David E Clouthier

An early requirement for nkx2.5 ensures the first and second heart field ventricular identity and cardiac function into adulthood

Developmental Biology, 400(1): 10-22, 2015. (PMID: 25536398)
Vanessa George, Sophie Colombo, Kimara L. Targoff

Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

DACS Chemical Biology, 10(3): 901-8, 2015. (PMID: 25560305)
Lu Wei, Yihui Shen, Fang Xu, Fanghao Hu, Jamie K. Harrington, Kimara L. Targoff, Wei Min

Nkx genes are essential for maintenance of ventricular identity

Development, 140(20): 4203-13, 2013. (PMID: 24026123)   
Kimara L. Targoff, Sophie Colombo, Vanessa George, Thomas Schell, Seok-Hyung Kim, Lilianna Solnica-Krezel, Deborah Yelon

UV microspot irradiator at Columbia University

Radiation and Environmental Biophysics, 52(3): 411-7, 2013. (PMID: 23708525)
Alan W Bigelow, Brian Ponnaiya, Kimara L. Targoff, David J Brenner

Nkx genes regulate heart tube extension in zebrafish and exert differential effects on ventricular and atrial cell number

Science Advances, 9(7): 4814, 2023.  (PMID: 36800428)
Nicola de Prisco, Caitlin Ford, Nathan D Elrod, Winston Lee, Lauren C Tang, Kai-Lieh Huang, Ai Lin, Ping Ji, Venkata S Jonnakuti, Lia Boyle, Maximilian Cabaj, Salvatore Botta, Katrin Õunap, Karit Reinson, Monica H Wojcik, Jill A Rosenfeld, Weimin Bi, Kristian Tveten, Trine Prescott, Thorsten Gerstner, Audrey Schroeder, Chin-To Fong, Jaya K George-Abraham, Catherine A Buchanan, Andrea Hanson-Khan, Jonathan A Bernstein, Aikaterini A Nella, Wendy K Chung, Vicky Brandt, Marko Jovanovic, Kimara L Targoff, Hari Krishna Yalamanchili, Eric J Wagner, Vincenzo A Gennarino

Nature Communications, 13(1): 2970, 2022.  (PMID: 35624100)
Carmen de Sena-Tomás, Angelika G Aleman, Caitlin Ford, Akriti Varshney, Di Yao, Jamie K Harrington, Leonor Saúde, Mirana Ramialison, Kimara L Targoff

Nature Communications, 11: 2141 (2020)
Kumi Morikawa, Kazuhiro Furuhashi, Carmen de Sena-Tomás, Alvaro L. Garcia-Garcia, Ramsey Bekdash, Alison D. Klein, Nicholas Gallerani, Hannah E. Yamamoto, Seon-Hye E. Park, Grant S. Collins, Fuun Kawano, Moritoshi Sato, Chyuan-Sheng Lin, Kimara L. Targoff, Edmund Au, Michael C. Salling & Masayuki Yazawa

Developmental Biology, 462(2): 223-234, 2020.  (PMID: 32272116)
Terin E Budine, Carmen de Sena-Tomás, Margot L K Williams, Diane S Sepich, Kimara L. Targoff, Lila Solnica-Krezel

Developmental Biology 322(2):  314-321, 2008. (PMID: 18718462)   
Kimara L. Targoff, Thomas Schell, Deborah Yelon